Compare One-Way Car Rentals

Planning a drive from San Francisco (CA) to San Diego (CA)? Compare quotes from multiple brands with no booking fees. It's also possible to take the opposite journey – from San Diego to San Francisco.

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Attractions Along the Road

From SF's foggy hugs to SD's sunny shrugs — a Golden State glow-up awaits! 🌞

San Francisco to San Diego

San Francisco
  • Golden Gate Bridge
  • Alcatraz Island
  • Fisherman's Wharf
Along the Way
  • Half Moon Bay
  • Santa Cruz Boardwalk
  • Monterey Bay Aquarium
  • 17-Mile Drive, Pebble Beach
  • Big Sur (Bixby Creek Bridge, McWay Falls)
  • Hearst Castle, San Simeon
  • Pismo Beach
  • Solvang (Danish Village)
  • Santa Barbara
Los Angeles Area
  • Griffith Observatory
  • Hollywood Walk of Fame
  • Santa Monica Pier
  • Venice Beach
San Diego
  • Balboa Park
  • San Diego Zoo
  • USS Midway Museum
  • La Jolla Cove
  • Gaslamp Quarter

One-Way Travel Questions

How far is it from San Francisco to San Diego?

It's 503 miles (810 km) from San Francisco to San Diego when driving along the I-5 S, which takes about 8 hours to drive. Alternatively, it's about 553 miles (890 km) when driving the US-101 S, which takes around 9.5 hours.

Can I rent a luxury car for a trip from San Francisco to San Diego?

Yes, you can rent a luxury car from San Francisco to San Diego through several car rental companies, including Enterprise, National, Alamo, Sixt, Avis, and Budget. Available models typically include the Audi A4, BMW 3 Series, and Chrysler 300.

Can I rent a people carrier for a one-way trip from San Francisco to San Diego? What vehicle models and rental companies are available on Road Genius?

Yes, you can rent a people carrier for a one-way trip from San Francisco to San Diego. Available models include the Chevrolet Suburban, Chevrolet Traverse, and Chrysler Pacifica from companies like Hertz, Sixt, Dollar, Thrifty, National, and Budget.

Can I rent an SUV for a one-way trip from San Francisco to San Diego?

Yes, you can rent an SUV for a one-way trip along the California coast. Popular models like the BMW X1, Chevrolet Tahoe, and Toyota RAV4 are available from rental companies such as Sixt, Hertz, and Enterprise.